In-situ Adhesion Studies of a Single Living Bovine Endothelial Cell Using Mems Sensor
نویسندگان
چکیده
Although previous studies of the adhesion properties of single living cells have been conducted a full understanding has still not been attained. In this article a MEMS sensor has been employed to study, quantitatively and qualitatively, the adhesion properties of a single living bovine endothelial cell. The strength of a single focal adhesion site to an extracellular matrix coated substrate is found to be 37 niv. Focal adhesion sites have been observed, insitu: to be spaced on the order of 1 pm intervals. A model is also proposed to describe the mechanism of detachment of a single Eiving cell from a substrate.
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